Ĭommon side effects when used as a cream are limited to the skin and include skin redness, peeling, and sun sensitivity. Topical tretinoin is also the most extensively investigated retinoid therapy for photoaging. For leukemia, it is taken by mouth for up to three months. For acne, it is applied to the skin as a cream, gel or ointment. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.Tretinoin, also known as all- trans retinoic acid ( ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The table below contains some of the most common ones associated with rub-on tretinoin preparations. It is common to need maintenance treatment for a number of years to keep acne away.Ĭan tretinoin solution or gel cause problems?Īlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Your doctor will recommend a suitable preparation for you to use. To prevent this, it is usual to carry on with a maintenance treatment after your spots have gone. Once your spots have cleared, acne commonly flares up again if you stop treatment.If necessary, discuss with your doctor which types of contraception are suitable for you and your partner. You should avoid getting pregnant while you are using tretinoin as there is a slight risk of harm to unborn babies.If there is no improvement despite having used it for eight weeks, speak with your doctor again as there are other treatments which could be more suited to your condition. The most common reason for treatment failure is stopping treatment too soon thinking it is not working. It is normal for tretinoin treatment to take several weeks before there is a noticeable improvement in your skin.A sun protection cream can help if you are out in the sun on bright days, even if it is cloudy. Tretinoin can make your skin more sensitive to sunlight than usual.Try to avoid any skin products which exfoliate or dry your skin. You can use make-up and moisturisers, but do not apply them at the same time as you use tretinoin.Do not use ointments or oil-rich creams, as these could clog your pores again. If your skin becomes very dry, it may help to use a moisturising cream (preferably a fragrance-free and water-based cream). The black tip of a blackhead is actually a skin pigment and cannot be removed by cleaning or scrubbing. It is recommended that you use a mild soap and lukewarm water to wash with, as very hot or cold water can worsen acne.Try not to let it build up in the folds or creases of your skin. Also, try to avoid getting it on the sensitive areas of your skin in or around your nostrils, your eyes and your mouth. Do not use tretinoin on any areas of your skin which are sunburnt or sore.If you have recently been using a preparation for your acne that causes your skin to peel, allow your skin to recover for a few days before you start using tretinoin.Remember to wash your hands after you have finished applying the solution/gel. Treclin® gel is applied once daily at bedtime. It is usual to apply the solution (Aknemycin® Plus) once or twice a day. A general point is that you should apply it to all of the area where your spots occur and not just to each spot. It is best if you wash and gently dry the affected areas of your skin before you apply it. Apply tretinoin exactly as your doctor tells you to.It will give you more information about tretinoin and will provide you with a full list of the side-effects which you may experience from using it. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Treclin® gel contains an antibacterial agent called clindamycin. Aknemycin® Plus solution also contains an antibacterial agent called erythromycin. Two brands of rub-on tretinoin are currently available. It also has an effect on reducing inflammation. In acne, some of these pores become blocked, causing small pimples, blackheads and whiteheads (comedones).Īpplying tretinoin to the areas of your skin with acne will help to unblock pores and treat blackheads or whiteheads. Tiny pores on your skin allow the sebum to come on to the surface of your skin. Small sebaceous glands lie just under your skin surface and make an oil (sebum) that keeps your skin supple and smooth. Most people with acne are aged between 12 and 25, but some older and younger people are affected too. Aknemycin® Plus (contains tretinoin with erythromycin) Treclin® (contains tretinoin with clindamycin)Īcne is the common cause of spots.
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